| ID | DRAMP21420 |
|---|---|
| Sequence | FLPKLFAKITKKNMAHIRC |
| Length | 19 |
| Name | AY1C (Derived from AY1) |
| Source | synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram- |
| Pathogen | [Ref.30872680] Gram-negative bacteria:Pseudomonas aeruginosa (MIC=15μM), Escherichia coli (MIC=17μM), Salmonella typhi(MIC=15μM), Klebsiella pneumoniae(MIC=12μM) |
| Hemolytic Activity | [Ref.30872680] 4% hemolysis at 10 μM, 9% hemolysis at 50 μM, 8% hemolysis at 100μM against human red blood cells |
| Cytotoxicity | [Ref.30872680] No cytotoxicity information found. |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | 5YKL resolved by NMR |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 30872680 |
Physicochemical Properties
| Residues | 19 |
|---|---|
| Sequence | FLPKLFAKITKKNMAHIRC |
| Molecular Weight | 2259.824 |
| Grand Average of Hydropathy | 0.058 |
| Isoelectric Point | 10.479 |
| Charge at pH 7.4 | 4.56 |
| Secondary Structure | Helix: 0.316, Turn: 0.105, Sheet: 0.263 |
| Instability Index | 35.826 |
| Aromaticity | 0.105 |