Basic Information
| ID | DRAMP29047 |
|---|
| Sequence | ARLDVASEFRKKWNKWALSR |
|---|
| Length | 20 |
|---|
| Name | PAMP (Proadrenomedullin N-terminal 20 peptide) |
|---|
| Source | Homo sapiens et.al |
|---|
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
|---|
| Pathogen | [Ref.32439180] Gram-negative bacteria: E. coli (MIC = 8 μM), P. aeruginosa (MIC = 32 μM), S. typhimurium (MIC = 16 μM)##Gram-positive bacteria:B. subtilis (MIC = 8 μM), S. epidermidis (MIC = 8 μM), S. aureus(MIC = 16 μM) |
|---|
| Hemolytic Activity | [Ref.32439180]HC10 > 256 μM against sheep RBCs.Note: HC10 is the minimum peptide concentration that caused >10% hemolysis of sheep red blood cells. |
|---|
| Cytotoxicity | Not found |
|---|
| N-terminal Modification | Free |
|---|
| C-terminal Modification | Amidation |
|---|
| Linear/Cyclic/Branched | Linear |
|---|
| Uniprot |
P35318, E9PML4, L5L428 |
|---|
| PDB |
2FLY |
|---|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 32439180 |
|---|
