Basic Information

IDDRAMP21188
SequenceGANLAKKFYTYINKFINYAW
Length20
NameGW-Q3 (De novo synthesis)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.18586467] Gram-positive bacteria : Staphylococcus aureus (BCRC 10780)(MIC=128 μg/ml), Staphylococcus xylosus (BCRC 12930)(MIC=64 μg/ml), Staphylococcus aureus (BCRC 10781)(MIC=128 μg/ml), Listeria monocytogenes (BCRC 14845)(MIC=128 μg/ml), Streptococcus bovis (BCRC 14729)(MIC=256 μg/ml), Streptococcus iniae (laboratory strain)(MIC=256 μg/ml), Lactococcus garvieae (laboratory strain)(MIC=256 μg/ml);##Gram-negative bacteria : Klebsiella oxytoca (BCRC 13985)(MIC=128 μg/ml), Pseudomonas aeruginosa (BCRC 10944)(MIC=128 μg/ml), Escherichia coli (BCRC 10675)(MIC=64 μg/ml), Enterobacter aerogenes (BCRC 10370)(MIC=32 μg/ml), Enterobacter cloacae (BCRC 10401)(MIC=64 μg/ml), Yersinia enterocolitica (BCRC 13999)(MIC=128 μg/ml)
Hemolytic Activity[Ref.18586467] MHC=128 μM against human red blood cells
Cytotoxicity[Ref.18586467] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID18586467

Physicochemical Properties

Residues20
SequenceGANLAKKFYTYINKFINYAW
Molecular Weight2425.779
Grand Average of Hydropathy-0.215
Isoelectric Point9.701
Charge at pH 7.42.542
Secondary StructureHelix: 0.450, Turn: 0.200, Sheet: 0.200
Instability Index40.99
Aromaticity0.3

Similar Structure Search

Candidates based on structure

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