| ID | DRAMP29053 |
|---|---|
| Sequence | AKLIPTIAL |
| Length | 9 |
| Name | RcAlb-PepI (designed in silico using as template the amino acid sequence of Rc-2S-Alb) |
| Source | Synthetic construct (Rc-2S-Alb comes from Ricinus communis (Castor bean)) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
| Pathogen | [Ref.31678367] Gram-negative bacteria: E. coli (MIC50 = 102 μM, MIC90 > 250 μM, MBC > 250 μM), K. pneumoniae(MIC50 = 121 μM, MIC90 > 250 μM, MBC > 250 μM)##Gram-positive bacteria: S. aureus (MIC50 = 123 μM, MIC90 > 250 μM, MBC > 250 μM)##Yeast: C. albicans (MIC50 = 62 μM, MIC90 > 250 μM, MFC > 250 μM), C. parapsilosis (MIC50 = 14 μM, MIC90 = 32 μM, MFC = 103 μM), C. tropicalis (MIC50 = 21 μM, MIC90 = 38 μM, MFC = 127 μM) |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not found |
| N-terminal Modification | Free |
| C-terminal Modification | Free |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 31678367 |
Physicochemical Properties
| Residues | 9 |
|---|---|
| Sequence | AKLIPTIAL |
| Molecular Weight | 939.193 |
| Grand Average of Hydropathy | 1.556 |
| Isoelectric Point | 8.795 |
| Charge at pH 7.4 | 0.605 |
| Secondary Structure | Helix: 0.444, Turn: 0.111, Sheet: 0.444 |
| Instability Index | -3.744 |
| Aromaticity | 0 |