| ID | DRAMP29140 |
|---|---|
| Sequence | FIGALLRPALKLLA |
| Length | 14 |
| Name | Pxt‐2 |
| Source | Xenopus tropicalis |
| Activity | Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Antifungal |
| Pathogen | [Ref.25312021]Gram-negative bacteria:Escherichia coli DH5α(MIC=50 µg/ml);##Gram-positive bacteria:Staphylococcus aureus JCM 2151(MIC=9.7 µg/ml).##[Ref.26802742]Gram-negative bacteria:Escherichia coli NBRC 14237(MIC<12.5 µM);Pseudomonas aeruginosa NBRC 12582(MIC<50 µM);##Gram-positive bacteria:Staphylococcus aureus NBRC 12732(MIC<12.5 µM);Micrococcus luteus NBRC 12708(MIC<25 µM);##Fungi:Saccharomyces cerevisiae NBRC 10217(ND);Candida albicans NBRC 1594(ND). |
| Hemolytic Activity | [Ref.25312021]0.4% Hemolysis against Rat erythrocytes at 20 µM.##[Ref.26802742]2% Hemolysis against Rat erythrocytes at 50 µM. |
| Cytotoxicity | [Ref.25312021]No cytotoxicity information found. |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 25312021, 26802742 |
Physicochemical Properties
| Residues | 14 |
|---|---|
| Sequence | FIGALLRPALKLLA |
| Molecular Weight | 1495.893 |
| Grand Average of Hydropathy | 1.521 |
| Isoelectric Point | 11.001 |
| Charge at pH 7.4 | 1.555 |
| Secondary Structure | Helix: 0.500, Turn: 0.143, Sheet: 0.571 |
| Instability Index | 32.364 |
| Aromaticity | 0.071 |
