| ID | dbAMP04075 |
|---|---|
| Sequence | GSKKPVPIIYCNRRATGKCQRM |
| Length | 22 |
| Name | Thanatin 4, Thanatin [A15insert]&&Th4 |
| Source | |
| Activity | Antibacterial |
| Pathogen | RBCs Source of Human (0% hemolysis at 20.8µM (non-hemolytic))&&Pseudomonas aeruginosa ATCC 27853 (MBC=4.0±0.0µM)&&Human myelogenous leukemia K562/ADM (IC50=32.6±3.4µM)&&Human myelogenous leukemia K562 (IC50=30.4±2.7µM)&&Human breast adenocarcinoma MCF-7/A |
| Hemolytic Activity | Not included yet |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 12297012 |
Physicochemical Properties
| Residues | 22 |
|---|---|
| Sequence | GSKKPVPIIYCNRRATGKCQRM |
| Molecular Weight | 2507.014 |
| Grand Average of Hydropathy | -0.777 |
| Isoelectric Point | 10.467 |
| Charge at pH 7.4 | 5.498 |
| Secondary Structure | Helix: 0.182, Turn: 0.273, Sheet: 0.091 |
| Instability Index | 38.518 |
| Aromaticity | 0.045 |