Basic Information

IDdbAMP04074
SequenceGSKKPVPIIYCNRRAATGKCQRM
Length23
NameThanatin 3, Thanatin [A15,16insert]&&Th5
Source
ActivityAntibacterial
PathogenStaphylococcus aureus DSM 1104 (MIC=40µM)&&RBCs Source of Human (0% hemolysis at 20.8µM (non-hemolytic))&&Pseudomonas aeruginosa DSM 1117 (MIC=5µM)&&Human hepatocellular carcinoma HepG2 (IC50=27.9±3.1µM)&&Escherichia coli DSM 1103 (MIC=2.5-5µM)&&Bacillus
Hemolytic ActivityNot included yet
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12297012

Physicochemical Properties

Residues23
SequenceGSKKPVPIIYCNRRAATGKCQRM
Molecular Weight2578.092
Grand Average of Hydropathy-0.665
Isoelectric Point10.467
Charge at pH 7.45.498
Secondary StructureHelix: 0.174, Turn: 0.261, Sheet: 0.130
Instability Index37.278
Aromaticity0.043

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