| ID | dbAMP22947 |
|---|---|
| Sequence | GWGSFFKKAAHVAKHVAKAALTHYL |
| Length | 25 |
| Name | [A13,17]Ple&&Pleurocidin [G13A][G17A]&&Ple-AA |
| Source | |
| Activity | Antibacterial |
| Pathogen | Staphylococcus epidermidis KCTC 1917 (MIC=0.5µM)&&Staphylococcus aureus KCTC 1621 (MIC=0.5µM)&&Staphylococcus aureus IFO 12732 (MIC=4µg/ml)&&Salmonella typhimurium KCTC 1926 (MIC=1µM)&&RBCs Source of Rabbit (50% hemolysis at 100µM)&&RBCs Source of Human ( |
| Hemolytic Activity | Not included yet |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 11168895, 11168895, 14965277 |
Physicochemical Properties
| Residues | 25 |
|---|---|
| Sequence | GWGSFFKKAAHVAKHVAKAALTHYL |
| Molecular Weight | 2739.181 |
| Grand Average of Hydropathy | 0.108 |
| Isoelectric Point | 10.177 |
| Charge at pH 7.4 | 3.655 |
| Secondary Structure | Helix: 0.320, Turn: 0.120, Sheet: 0.320 |
| Instability Index | 18.556 |
| Aromaticity | 0.16 |