| ID | dbAMP22948 |
|---|---|
| Sequence | AWASFFKKAAHVAKHVAKAALTHYL |
| Length | 25 |
| Name | [A1,3,13,17]Ple&&Pleurocidin [G1A][G3A][G13A][G17A] |
| Source | |
| Activity | Antibacterial |
| Pathogen | Staphylococcus aureus IFO 12732 (MIC=2µg/ml)&&RBCs Source of Rabbit (45% hemolysis at 100µM)&&RBCs Source of Human (90% hemolysis at 100µM)&&Pseudomonas aeruginosa IFO 12582 (MIC=4µg/ml)&&Escherichia coli IFO 12734 (MIC=2µg/ml)&&Bacillus subtilis IFO 3143 |
| Hemolytic Activity | Not included yet |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 11168895, 11168895 |
Physicochemical Properties
| Residues | 25 |
|---|---|
| Sequence | AWASFFKKAAHVAKHVAKAALTHYL |
| Molecular Weight | 2767.235 |
| Grand Average of Hydropathy | 0.284 |
| Isoelectric Point | 10.177 |
| Charge at pH 7.4 | 3.705 |
| Secondary Structure | Helix: 0.320, Turn: 0.040, Sheet: 0.400 |
| Instability Index | 11.756 |
| Aromaticity | 0.16 |