Basic Information

IDDRAMP00038
SequenceITSKSLCTPGCKTGILMTCPLKTATCGCHFG
Length31
NameNisin U (Bacteriocin)
SourceLactococcus uberis ATCC 27958
ActivityAntimicrobial, Antibacterial, Anti-Gram+
PathogenGram-positive bacteria: Streptococcus pyogenes, Streptococcus uberis, Streptococcus agalactiae, Streptococcus dysgalactiae, Staphylococcus simulans, Staphylococcus cohnii, Lactococcus lactis, Lactobacillus acidophilus, Streptococcus mitis.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot Q2QBT0
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16461661

Physicochemical Properties

Residues31
SequenceITSKSLCTPGCKTGILMTCPLKTATCGCHFG
Molecular Weight3173.835
Grand Average of Hydropathy0.448
Isoelectric Point8.78
Charge at pH 7.42.464
Secondary StructureHelix: 0.194, Turn: 0.258, Sheet: 0.161
Instability Index30.645
Aromaticity0.032

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