Basic Information

IDDRAMP01089
SequenceGFKEVLKAGLGSLVKGIPAHVAN
Length23
NameAlyteserin-1Mb (toads, amphibians, animals)
SourceAlytes maurus (Midwife toad)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacterium: Escherichia coli NCTC 10418 (MIC=217 µM) and Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=434 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal Modificationα-Amidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22800568

Physicochemical Properties

Residues23
SequenceGFKEVLKAGLGSLVKGIPAHVAN
Molecular Weight2305.717
Grand Average of Hydropathy0.47
Isoelectric Point9.703
Charge at pH 7.41.588
Secondary StructureHelix: 0.348, Turn: 0.304, Sheet: 0.304
Instability Index-5.865
Aromaticity0.043

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