Basic Information

IDDRAMP01177
SequenceGVVDILKGAAKDIAGHLASKVMNKL
Length25
NameOcellatin-F1 (Fallaxin; Frogs, amphibians, animals)
SourceLeptodactylus fallax (Mountain chicken frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram-
Pathogen[Ref.15544856]Gram-negative bacteria: Escherichia coli (MIC=40 µM), Pseudomonas aeruginosa (MIC=80 µM), Enterobacter cloacae (MIC=20 µM), Klebsiella pneumoniae (MIC=80 µM).
Hemolytic Activity[Ref:15544856]HC50>200 μM hemolytic activity of fallaxin
Cytotoxicity[Ref.15544856]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15544856

Physicochemical Properties

Residues25
SequenceGVVDILKGAAKDIAGHLASKVMNKL
Molecular Weight2549.041
Grand Average of Hydropathy0.432
Isoelectric Point9.528
Charge at pH 7.41.585
Secondary StructureHelix: 0.320, Turn: 0.200, Sheet: 0.320
Instability Index3.784
Aromaticity0

Similar Structure Search

Candidates based on structure

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