Basic Information
| ID | DRAMP01879 |
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| Sequence | GAFGDLLKGVAKEAGMKLLNMAQCKLSGKC |
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| Length | 30 |
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| Name | Brevinin-2LTa (Frogs, amphibians, animals) |
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| Source | Hylarana latouchii (Broad-folded frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=2 µM), Bacillus licheniformis X39 (MIC=8 µM), Staphylococcus carnosus KHS (MIC=2 µM), Rhodococcus rhodochrous X15 (MIC=0.5 µM);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=32.5 µM), Serratia rubidaea X01 (MIC=130 µM), Pseudomonas aeruginosa 1.50 (MIC=65 µM), Psychrobacter faecalis X29 (MIC=0.5 µM). |
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| Hemolytic Activity | [Ref.22426384] LD50=520 μM against human erythrocytes |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys24 and Cys30) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 22426384 |
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