Basic Information

IDDRAMP01182
SequenceGLLDTLKGAAKNVVGSLASKVMEKL
Length25
NameOcellatin-P1 (Pentadactylin; Frogs, amphibians, animals)
SourceLeptodactylus pentadactylus (South American bullfrog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli ATCC 25922 (MIC=25 µM), Klebsiella pneumoniae KK3 9904 (MIC=100 µM), Enterobacter cloacae HNTCC 53001 (MIC=50 µM), Pseudomonas aeruginosa ATCC 27853 (MIC=100 µM);##Gram-positive bacteria: Staphylococcus epidermidis RP62A (MIC=100 µM), Streptococcus Group B HNTCC 80130 (MIC=50 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.16236555]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16236555

Physicochemical Properties

Residues25
SequenceGLLDTLKGAAKNVVGSLASKVMEKL
Molecular Weight2543.032
Grand Average of Hydropathy0.372
Isoelectric Point9.528
Charge at pH 7.41.549
Secondary StructureHelix: 0.320, Turn: 0.240, Sheet: 0.400
Instability Index-16.788
Aromaticity0

Similar Structure Search

Candidates based on structure

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