Basic Information

IDDRAMP02252
SequenceGLLDAIKDTAQNLFANVLDKIKCKFTKC
Length28
NameRanatuerin 2SKa (Frogs, amphibians, animals)
SourceRana sakuraii (Japanese brown frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacterium: Escherichia coli (MIC=50 µM);##Gram-positive bacterium: Staphylococcus aureus (MIC>50 µM).##Yeast: Candida albicans (MIC>50 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys23 and Cys28)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17174009

Physicochemical Properties

Residues28
SequenceGLLDAIKDTAQNLFANVLDKIKCKFTKC
Molecular Weight3111.676
Grand Average of Hydropathy0.075
Isoelectric Point8.788
Charge at pH 7.41.497
Secondary StructureHelix: 0.321, Turn: 0.107, Sheet: 0.250
Instability Index-7.854
Aromaticity0.071

Similar Structure Search

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