Basic Information
| ID | DRAMP01218 |
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| Sequence | GFMKYIGPLIPHAVKAISDLI |
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| Length | 21 |
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| Name | Kassinatuerin-1 (Frogs, amphibians, animals) |
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| Source | Kassina senegalensis (Senegal running frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | Gram-negative bacteria: Escherichia coli (MIC=6.25 µM), Klebsiella pneumoniae (MIC=25 µM), Enterobacter cloacae (MIC=6.25 µM), Pseudomonas aeruginosa (MIC=25 µM);##Gram-positive bacteria: Staphylococcus aureus (MIC=6.25 µM), Staphylococcus epidermidis (MIC=6.25 µM), Enterococcus faecalis (MIC=12.5 µM).##Yeast: Candida albicans (MIC=100 µM). |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | [Ref.15885852]Display cytotoxicity against L929 fibroblasts (LD50=12μM). |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
P0C010 |
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| PDB |
|
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 10679222, 15885852 |
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