Basic Information

IDDRAMP21254
SequenceFLFKLIPKVIKGLVKAIRK
Length19
NameAaeAP2a (Derived from AaeAP2)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.25626077] Gram-positive bacteria : Staphylococcus aureus(MIC=4 mg/L, MBC=32 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=16 mg/L, MBC=32 mg/L);##Fungi : Candida albicans(MIC=4 mg/L, MBC=16 mg/L)
Hemolytic Activity[Ref.25626077] 100% hemolysis at 64 μg/ml against horse red blood cells
Cytotoxicity[Ref.25626077] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID25626077

Physicochemical Properties

Residues19
SequenceFLFKLIPKVIKGLVKAIRK
Molecular Weight2211.862
Grand Average of Hydropathy0.774
Isoelectric Point11.388
Charge at pH 7.45.545
Secondary StructureHelix: 0.526, Turn: 0.105, Sheet: 0.211
Instability Index-19.342
Aromaticity0.105

Similar Structure Search

Candidates based on structure

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