Basic Information

IDDRAMP21253
SequenceFLFKLIPKAIKGLVKAIRK
Length19
NameAaeAP1a (Derived from AaeAP1)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.25626077] Gram-positive bacteria : Staphylococcus aureus(MIC=4 mg/L, MBC=32 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=16 mg/L, MBC=32 mg/L);##Fungi : Candida albicans(MIC=4 mg/L, MBC=16 mg/L)
Hemolytic Activity[Ref.25626077] 100% hemolysis at 32 μg/ml against horse red blood cells
Cytotoxicity[Ref.25626077] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID25626077

Physicochemical Properties

Residues19
SequenceFLFKLIPKAIKGLVKAIRK
Molecular Weight2183.809
Grand Average of Hydropathy0.647
Isoelectric Point11.388
Charge at pH 7.45.545
Secondary StructureHelix: 0.474, Turn: 0.105, Sheet: 0.263
Instability Index-14.874
Aromaticity0.105

Similar Structure Search

Candidates based on structure

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