Basic Information

IDDRAMP01245
SequenceFFPLALLCKVFKKC
Length14
NameJaponicin-1CDYa (Frogs, amphibians, animals)
SourceRana dybowskii (Dybovsky's frog) (Korean brown frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.19539775]Gram-positive bacterium: Staphylococcus aureus (MIC>100 µM);##Gram-negative bacterium: Escherichia coli (MIC=25 µM).
Hemolytic Activity[Ref:19539775] HC50>300 μM against human red blood cells
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys8 and Cys14)
Linear/Cyclic/BranchedCyclic
Uniprot B3VZU2
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19539775

Physicochemical Properties

Residues14
SequenceFFPLALLCKVFKKC
Molecular Weight1657.136
Grand Average of Hydropathy1.25
Isoelectric Point9.39
Charge at pH 7.42.501
Secondary StructureHelix: 0.500, Turn: 0.071, Sheet: 0.286
Instability Index6.243
Aromaticity0.214

Similar Structure Search

Candidates based on structure

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