Basic Information

IDDRAMP01255
SequenceSAVGRHGRRFGLRKHRKH
Length18
NameDybowskin-2CDYa (Chensinin-1; Frogs, amphibians, animals)
SourceRana dybowskii (Dybovsky's frog) (Korean brown frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.19539775] Gram-negative bacterium: Escherichia coli (MIC=3 µM);##Gram-negative bacterium: Staphylococcus aureus (MIC=6 µM).##[Ref.19341344] Gram-positive bacteria: Staphylococcus aureus (MIC=14.4 µM), Bacillus cereus (MIC=14.4 µM), Streptococcus lactis (MIC=14.4 µM).
Hemolytic Activity[Ref:19539775]HC50>300 μM against human red blood cells
Cytotoxicity[Ref.19539775]No cytotoxicity information found##[Ref.19341344]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot B5A9T1
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19539775, 19341344

Physicochemical Properties

Residues18
SequenceSAVGRHGRRFGLRKHRKH
Molecular Weight2155.478
Grand Average of Hydropathy-1.628
Isoelectric Point12
Charge at pH 7.46.358
Secondary StructureHelix: 0.167, Turn: 0.222, Sheet: 0.111
Instability Index52.189
Aromaticity0.056

Similar Structure Search

Candidates based on structure

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