Basic Information

IDDRAMP01339
SequenceFLPIVGKLLSGLSGLL
Length16
NameAmolopin-2a (Frogs, amphibians, animals)
SourceAmolops loloensis (Rufous-spotted torrent frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacteria: Staphylococcus aureus (MIC=2.00 µg/ml), Bacillus dysenteriae (MIC=1.50 µg/ml);##Gram-negative bacterium: Escherichia coli (MIC=3.00 µg/ml).##Candida albicans (MIC=6.50 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.17000029]Display cytotoxicity against HepG2(IC50=77 mg/ml).
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17000029

Physicochemical Properties

Residues16
SequenceFLPIVGKLLSGLSGLL
Molecular Weight1627.019
Grand Average of Hydropathy1.625
Isoelectric Point8.75
Charge at pH 7.40.555
Secondary StructureHelix: 0.562, Turn: 0.375, Sheet: 0.375
Instability Index0.188
Aromaticity0.062

Similar Structure Search

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