| ID | DRAMP29072 |
|---|---|
| Sequence | GFGSLLGKAlrLwKkVL |
| Length | 17 |
| Name | CPF-15 (Variant of CPF-C1) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+ |
| Pathogen | [Ref.32590058] Gram-positive: S. aureus ATCC 25923 (MIC = 64 μg/mL) |
| Hemolytic Activity | [Ref.32590058]It showed significant toxicity at high concentrations. CPF-15 displayed 5%, 12%, 23%, 50% and 67% at the concentrations of 8, 16, 32, 64, 128 μg/mL |
| Cytotoxicity | Not found |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 32590058 |
Physicochemical Properties
| Residues | 17 |
|---|---|
| Sequence | GFGSLLGKAlrLwKkVL |
| Molecular Weight | 1886.33 |
| Grand Average of Hydropathy | 0.512 |
| Isoelectric Point | 11.264 |
| Charge at pH 7.4 | 3.55 |
| Secondary Structure | Helix: 0.471, Turn: 0.235, Sheet: 0.353 |
| Instability Index | 24.682 |
| Aromaticity | 0.118 |