Basic Information

IDDRAMP01648
SequenceGLVTSLIKGAGKLLGGLFGSVTGGQS
Length26
NameDermaseptin-like PBN2 (DRP-PBN2; Plasticin-B1a; Frogs, amphibians, animals)
SourcePhyllomedusa bicolor (Two-colored leaf frog) (Rana bicolor)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Escherichia coli B (MIC=1.5 µM), Salmonella typhimurium (MIC=3.1 µM), Salmonella enteritidis (MIC=1.5 µM), Enterobacter cloacae (MIC=12.5 µM), Klebsiella pneumoniae (MIC=0.8 µM);##Gram-positive bacteria: Aerococcus viridans (MIC=3.1 µM), Bacillus megaterium (MIC=0.8 µM), Staphylococcus aureus (MIC=3.1 µM), Staphylococcus haemolyticus (MIC=0.8 µM).##Fungi: Saccaromyces cerevisiae (MIC=3.1 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.12709067]No cytotoxicity information found##[Ref.15222751]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot Q800R4
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12709067, 15222751

Physicochemical Properties

Residues26
SequenceGLVTSLIKGAGKLLGGLFGSVTGGQS
Molecular Weight2417.798
Grand Average of Hydropathy0.7
Isoelectric Point10.003
Charge at pH 7.41.552
Secondary StructureHelix: 0.346, Turn: 0.423, Sheet: 0.231
Instability Index9.885
Aromaticity0.038

Similar Structure Search

Candidates based on structure

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