Basic Information

IDDRAMP04011
SequenceGVVTDLLKTAGKLLGNLFGSLSG
Length23
NamePlasticin PD36 KF (analog of PD36)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.17128968]Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=6.5 µM), Bacillus megaterium ATCC 9885 (MIC=50.25 µM);##Gram-negative bacteria: Escherichia coli ATCC 11775 (MIC=6.5 µM), Salmonella typhimurium CIP 6062 (MIC=25.25 µM), Enterobacter cloacae ATCC 11775 (MIC=12.5 µM).
Hemolytic Activity[Ref.17128968]25% hemolytic at 50 μM, 50% hemolytic activity at 100 μM against rat red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17128968

Physicochemical Properties

Residues23
SequenceGVVTDLLKTAGKLLGNLFGSLSG
Molecular Weight2260.628
Grand Average of Hydropathy0.696
Isoelectric Point8.591
Charge at pH 7.40.553
Secondary StructureHelix: 0.391, Turn: 0.348, Sheet: 0.304
Instability Index-8.891
Aromaticity0.043

Similar Structure Search

Candidates based on structure

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