Basic Information

IDDRAMP01753
SequenceFVDLKKIANIINSIFGK
Length17
NameTemporin-1CEa (Frogs, amphibians, animals)
SourceRana chensinensis (Chinese brown frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.21871946]Gram-positive bacteria: Staphylococcus aureus (MIC=14.4 µM), Bacillus cereus (MIC=14.4 µM), Streptococcus lactis (MIC=14.4 µM);##Gram-negative bacterium: Escherichia coli (MIC>100 µM).
Hemolytic Activity[Ref:21871946]LD50=99.08 μM against human erythrocytes
Cytotoxicity[Ref.19341344]No cytotoxicity information found##[Ref.21871946]No determined cytotoxic against SMCs at the concentration between 20-60 μM.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID21871946, 19341344

Physicochemical Properties

Residues17
SequenceFVDLKKIANIINSIFGK
Molecular Weight1920.298
Grand Average of Hydropathy0.588
Isoelectric Point9.703
Charge at pH 7.41.55
Secondary StructureHelix: 0.471, Turn: 0.235, Sheet: 0.118
Instability Index11.435
Aromaticity0.118

Similar Structure Search

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