Basic Information

IDDRAMP01812
SequenceFLPVLAGVLSRA
Length12
NameTemporin-Rb (Frogs, amphibians, animals)
SourceRana ridibunda (marsh frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Streptococcus dysgalactiae PTCC 1074 (MIC=21.8 µg/ml), Streptococcus agalactiae PTCC 1365 (MIC=30.5 µg/ml), Staphylococcus aureus PTCC 1431 (MIC=42.1 µg/ml), Staphylococcus typhimurium (MIC=31.8 µg/ml);##Gram-negative bacteria: Escherichia coli (MIC=34.5 µg/ml), Klebsiella pneumoniae PTCC 1388 (MIC=35.1 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.21956830]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID21956830

Physicochemical Properties

Residues12
SequenceFLPVLAGVLSRA
Molecular Weight1242.509
Grand Average of Hydropathy1.575
Isoelectric Point9.75
Charge at pH 7.40.557
Secondary StructureHelix: 0.500, Turn: 0.250, Sheet: 0.417
Instability Index57.317
Aromaticity0.083

Similar Structure Search

Candidates based on structure

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