Basic Information

IDDRAMP01870
SequenceFLPIIAGMAAKVICAITKKC
Length20
NameBrevinin-1SPb (Frogs, amphibians, animals)
SourceRana septentrionalis (mink frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.15556063]Gram-negative bacterium: Escherichia coli (MIC=50 µM);##Gram-positive bacterium: Staphylococcus aureus (MIC=13 µM);##Yeast: Candida albicans (MIC=25 µM).
Hemolytic Activity[Ref.15556063]HC50=25 µM against human erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15556063

Physicochemical Properties

Residues20
SequenceFLPIIAGMAAKVICAITKKC
Molecular Weight2091.689
Grand Average of Hydropathy1.425
Isoelectric Point9.39
Charge at pH 7.42.501
Secondary StructureHelix: 0.350, Turn: 0.100, Sheet: 0.300
Instability Index21.055
Aromaticity0.05

Similar Structure Search

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