Basic Information

IDDRAMP20905
SequenceFIHHIIGGLFSAGKAIHRLIR
Length21
NamedC4
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
Pathogen[Ref.29040295] Gram-positive bacteria: Staphylococcus aureus (MIC=64 μg/ml; MBC=128 μg/ml), Methicillin-resistant Staphylococcus aureus (MIC=256 μg/ml; MBC=256 μg/ml);##Fungi: Candida albicans (MIC=128 μg/ml; MBC=256 μg/ml)
Hemolytic Activity[Ref.29040295] 5% haemolysis at 12.50 μg/ml, 10% haemolysis at 25.00 μg/ml, 45% haemolysis at 50.00 μg/ml, 80% haemolysis at 100.00 μg/ml, 100% haemolysis at 200.00 μg/ml, 100% haemolysis at 400.00 μg/ml against mouse red blood cells
Cytotoxicity[Ref.29040295] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID29040295

Physicochemical Properties

Residues21
SequenceFIHHIIGGLFSAGKAIHRLIR
Molecular Weight2356.815
Grand Average of Hydropathy0.705
Isoelectric Point12
Charge at pH 7.42.665
Secondary StructureHelix: 0.429, Turn: 0.190, Sheet: 0.190
Instability Index44.033
Aromaticity0.095

Similar Structure Search

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