Basic Information

IDDRAMP20903
SequenceFIHHIIGGLFSAGKAIHRLIRRR
Length23
NamedC2
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.29040295] Gram-positive bacteria: Staphylococcus aureus (MIC=16 μg/ml; MBC=32 μg/ml), Methicillin-resistant Staphylococcus aureus (MIC=32 μg/ml; MBC=32 μg/ml);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=512 μg/ml; MBC>512 μg/ml);##Fungi: Candida albicans (MIC=128 μg/ml; MBC=128 μg/ml)
Hemolytic Activity[Ref.29040295] 2% haemolysis at 3.13 μg/ml, 5% haemolysis at 6.25 μg/ml, 25% haemolysis at 12.50 μg/ml, 65% haemolysis at 25.00 μg/ml, 90% haemolysis at 50.00 μg/ml, 100% haemolysis at 100.00 μg/ml against mouse red blood cells
Cytotoxicity[Ref.29040295] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID29040295

Physicochemical Properties

Residues23
SequenceFIHHIIGGLFSAGKAIHRLIRRR
Molecular Weight2669.186
Grand Average of Hydropathy0.252
Isoelectric Point12
Charge at pH 7.44.665
Secondary StructureHelix: 0.391, Turn: 0.174, Sheet: 0.174
Instability Index90.883
Aromaticity0.087

Similar Structure Search

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