Basic Information
| ID | DRAMP20900 |
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| Sequence | FIHHIIGGLFSIGKIIHRLIRRRRR |
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| Length | 25 |
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| Name | A12I/A15I |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.29040295] Gram-positive bacteria: Staphylococcus aureus (MIC=16 μg/ml; MBC=64 μg/ml), Methicillin-resistant Staphylococcus aureus (MIC=64 μg/ml; MBC=256 μg/ml);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=512 μg/ml; MBC>512 μg/ml);##Fungi: Candida albicans (MIC=128 μg/ml; MBC=128 μg/ml) |
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| Hemolytic Activity | [Ref.29040295] 0% haemolysis at 0.20 μg/ml, 5% haemolysis at 0.39 μg/ml, 25% haemolysis at 0.78 μg/ml, 85% haemolysis at 1.56 μg/ml, 95% haemolysis at 3.13 μg/ml, 100% haemolysis at 6.25 μg/ml against mouse red blood cells |
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| Cytotoxicity | [Ref.29040295] No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Free |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 29040295 |
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