Basic Information

IDDRAMP20899
SequenceFIHHAAGGLFSAGKAIHRLIRRRRR
Length25
NameI5A/I6A
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram-, Antifungal
Pathogen[Ref.29040295] Gram-negative bacteria: Pseudomonas aeruginosa (MIC=512 μg/ml; MBC=512 μg/ml);##Fungi: Candida albicans (MIC=128 μg/ml; MBC=128 μg/ml)
Hemolytic Activity[Ref.29040295] 5% haemolysis at 25.00 μg/ml, 7% haemolysis at 50.00 μg/ml, 10% haemolysis at 100.00 μg/ml, 40% haemolysis at 200.00 μg/ml, 80% haemolysis at 400.00 μg/ml, 100% haemolysis at 800.00 μg/ml against mouse red blood cells
Cytotoxicity[Ref.29040295] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID29040295

Physicochemical Properties

Residues25
SequenceFIHHAAGGLFSAGKAIHRLIRRRRR
Molecular Weight2897.398
Grand Average of Hydropathy-0.344
Isoelectric Point12
Charge at pH 7.46.665
Secondary StructureHelix: 0.280, Turn: 0.160, Sheet: 0.240
Instability Index112.66
Aromaticity0.08

Similar Structure Search

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