Basic Information

IDDRAMP02031
SequenceILPLLLGKVVCAITKKC
Length17
NameBrevinin-1Da (Frogs, amphibians, animals)
SourceRana dalmatina (European frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus (MIC=7 µM);##Gram-negative bacterium: Escherichia coli (MIC=30 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys11 and Cys17)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15050930

Physicochemical Properties

Residues17
SequenceILPLLLGKVVCAITKKC
Molecular Weight1812.374
Grand Average of Hydropathy1.471
Isoelectric Point9.39
Charge at pH 7.42.501
Secondary StructureHelix: 0.471, Turn: 0.118, Sheet: 0.294
Instability Index22.082
Aromaticity0

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.