Basic Information

IDDRAMP01898
SequenceFLSTLLNVASNVVPTLICKITKKC
Length24
NameBrevinin-1CG3 (Frogs, amphibians, animals)
SourceAmolops chunganensis (Chungan torrent frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacteria: Rhodococcus rhodochrous X15 (MIC=2.3 µM), Bacillus licheniformis X39 (IS) (MIC=9 µM), Enterococcus faecalis 981 (MIC=75 µM), Staphylococcus carnosus KHS (IS) (MIC=19 µM), Staphylococcus aureus (ATCC 25923) (MIC=19 µM);##Gram-negative bacteria: Escherichia coli (ATCC 25922) (MIC=150 µM), Psychrobacter faecalis X29 (IS) (MIC=4.5 µM), Serratia rubidaea X01 (IS) (MIC=9 µM).##Fungi: Slime mold 090223 (IS) (MIC=9 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22951323

Physicochemical Properties

Residues24
SequenceFLSTLLNVASNVVPTLICKITKKC
Molecular Weight2606.195
Grand Average of Hydropathy0.933
Isoelectric Point9.39
Charge at pH 7.42.501
Secondary StructureHelix: 0.417, Turn: 0.208, Sheet: 0.208
Instability Index14.071
Aromaticity0.042

Similar Structure Search

Candidates based on structure

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