Basic Information
| ID | DRAMP02073 |
|---|
| Sequence | FLPAVIRVAANVLPTVFCAISKKC |
|---|
| Length | 24 |
|---|
| Name | Brevinin-1JDa (Frogs, amphibians, animals) |
|---|
| Source | Odorrana jingdongensis (Jingdong frog) (Rana jingdongensis) |
|---|
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
|---|
| Pathogen | [Ref.22917879]Gram-positive bacteria: Staphylococcus aureus (MIC=16 µg/ml), S. aureus (MRSA) (MIC=32 µg/ml);##Gram-negative bacterium: Escherichia coli (MIC=128 µg/ml);##Fungi: Candida albicans (MIC=128 µg/ml). |
|---|
| Hemolytic Activity | [Ref.22917879] It has 79.2 ± 6.8% hemolytic activity at 128 μg/mL against rabbit red blood cells |
|---|
| Cytotoxicity | No cytotoxicity information found |
|---|
| N-terminal Modification | Free |
|---|
| C-terminal Modification | Cyclization (Cys18 and Cys24) |
|---|
| Linear/Cyclic/Branched | Cyclic |
|---|
| Uniprot |
B3A0M4 |
|---|
| PDB |
|
|---|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 22917879 |
|---|
