Basic Information

IDDRAMP02131
SequenceGVWSTVLGGLKKFAKGGLEAIVNPK
Length25
NameAntimicrobial peptide 2 (XT-2; Frogs, amphibians, animals)
SourceXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Staphylococcus aureus (MIC>100 µM);##Gram-negative bacteria: Escherichia coli (MIC=8 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P84382
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11738090

Physicochemical Properties

Residues25
SequenceGVWSTVLGGLKKFAKGGLEAIVNPK
Molecular Weight2570.037
Grand Average of Hydropathy0.252
Isoelectric Point10.001
Charge at pH 7.42.549
Secondary StructureHelix: 0.360, Turn: 0.320, Sheet: 0.240
Instability Index8.132
Aromaticity0.08

Similar Structure Search

Candidates based on structure

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