Basic Information

IDDRAMP02134
SequenceGMATKAGTALGKVAKAVIGAAL
Length22
NameAntimicrobial peptide 5 (XT-5; PGLa-like peptide; Frogs, amphibians, animals)
SourceXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.11738090]Gram-positive bacteria: Staphylococcus aureus (MIC>100 µM);##Gram-negative bacteria: Escherichia coli (MIC>100 µM);##Fungi: Candida albicans (MIC>100 µM)
Hemolytic Activity[Ref.11738090]HC50>150 μM against human erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P84385
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11738090

Physicochemical Properties

Residues22
SequenceGMATKAGTALGKVAKAVIGAAL
Molecular Weight1999.421
Grand Average of Hydropathy0.923
Isoelectric Point10.302
Charge at pH 7.42.55
Secondary StructureHelix: 0.227, Turn: 0.182, Sheet: 0.455
Instability Index-0.282
Aromaticity0

Similar Structure Search

Candidates based on structure

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