Basic Information

IDDRAMP02354
SequenceFFRLLFHGVHHGGGYLNAA
Length19
NamePleurocidin-like peptide WFY (fish, chordates, animals)
SourcePseudopleuronectes americanus (Winter flounder) (Pleuronectes americanus)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Aeromonas salmonicida A449 field isolate (MIC>64 µg/ml), A. salmonicida 97-4 field isolate (MIC>64 µg/ml), Pseudomonas aeruginosa K799 (MIC>64 µg/ml), Pseudomonas aeruginosa Z61 (MIC=64 µg/ml), Escherichia coli CGSC4908 triple (MIC=64 µg/ml), Salmonella typhimurium 14028s (MIC>64 µg/ml), Salmonella typhimurium MS7953s (MIC=64 µg/ml);##Gram-positive bacteria: Staphylococcus epidermidis (human clinical isolates) (MIC>64 µg/ml), Staphylococcus aureus (MRSA) (MIC>64 µg/ml).##Fungi: Candida albica (MIC>64 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12950255

Physicochemical Properties

Residues19
SequenceFFRLLFHGVHHGGGYLNAA
Molecular Weight2113.381
Grand Average of Hydropathy0.374
Isoelectric Point8.768
Charge at pH 7.40.665
Secondary StructureHelix: 0.421, Turn: 0.263, Sheet: 0.263
Instability Index7.079
Aromaticity0.211

Similar Structure Search

Candidates based on structure

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