Basic Information

IDDRAMP02364
SequenceGFWGKLFKLGLHGIGLLHLHL
Length21
NamePleurocidin-like peptide GcSc4B7 (NRC-15; fish, chordates, animals; Predicted)
SourceGlyptocephalus cynoglossus (Witch flounder GcSc4B7)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Aeromonas salmonicida 99-1 (MIC=8 µg/ml), A. salmonicida 97-4 (MIC=16 µg/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=4 µg/ml), S. enterica serovar Typhimurium 14028s (MIC=16 µg/ml), Pseudomonas aeruginosa K799 (MIC=8 µg/ml), Pseudomonas aeruginosa Z61 (MIC=4 µg/ml), Escherichia coli CGSC 4908 (MIC=8 µg/ml), E. coli UB1005 (MIC=8 µg/ml), E. coli DC2 (MIC=8 µg/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC=4 µg/ml), Staphylococcus aureus (MRSA) C623 (MIC=4 µg/ml).##Yeast: Candida albicans C627 (MIC=16 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q7SZG9
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12878506

Physicochemical Properties

Residues21
SequenceGFWGKLFKLGLHGIGLLHLHL
Molecular Weight2356.853
Grand Average of Hydropathy0.781
Isoelectric Point10.003
Charge at pH 7.41.662
Secondary StructureHelix: 0.524, Turn: 0.238, Sheet: 0.333
Instability Index-23.681
Aromaticity0.143

Similar Structure Search

Candidates based on structure

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