Basic Information

IDDRAMP02374
SequenceGCRFCCNCCPNMSGCGVCCRF
Length21
NameBass hepcidin (fish, chordates, animals)
SourceMorone chrysops x Morone saxatilis (white bass x striped sea-bass)
ActivityAntimicrobial, Antibacterial, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Escherichia coli ATCC 25,922,351,50 (MIC=22 µM), Escherichia coli ATCC D31K (MIC=11 µM), Klebsiella pneumoniae ATCC 10,031 (MIC=22 µM), P. shigelloides ATCC KST (MIC=11 µM), S. flexneri ATCC 12,022 (MIC=22 µM), Shigella sonnei ATCC 9290 (MIC=44 µM), Y. enterocolitica ATCC 23,715 (MIC=22 µM).##Fungi: Aspergillus niger (MIC=44 µM).
Hemolytic Activity[Ref.15546886] It displays essentially no hemolytic activity toward HSB erythrocytes
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot P82951
PDB 1S6W
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11985602, 15546886

Physicochemical Properties

Residues21
SequenceGCRFCCNCCPNMSGCGVCCRF
Molecular Weight2263.756
Grand Average of Hydropathy0.576
Isoelectric Point8.228
Charge at pH 7.41.361
Secondary StructureHelix: 0.143, Turn: 0.333, Sheet: 0.048
Instability Index38.248
Aromaticity0.095

Similar Structure Search

Candidates based on structure

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