Basic Information

IDDRAMP03564
SequenceICIFCCGCCHRSKCGMCCKT
Length20
NameHuman hepcidin-20 (Hepc20; one chain of Hepcidin; Human, mammals, animals)
SourceHomo sapiens (Human)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacterium: Escherichia coli;##Gram-positive bacteria: Staphylococcus aureus, S. epidermidis, group B Streptococcus.##Fungi: Candida albicans, Aspergillus fumigatus, Aspergillus niger.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P81172, Q1HE14, Q9BY68
PDB 1M4E
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11113131, 12138110, 11034317

Physicochemical Properties

Residues20
SequenceICIFCCGCCHRSKCGMCCKT
Molecular Weight2199.797
Grand Average of Hydropathy0.795
Isoelectric Point8.529
Charge at pH 7.42.393
Secondary StructureHelix: 0.150, Turn: 0.150, Sheet: 0.050
Instability Index47.77
Aromaticity0.05

Similar Structure Search

Candidates based on structure

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