Basic Information

IDDRAMP02861
SequenceQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR
Length41
NameBovine Beta-defensin 4 (bBD-4; BNBD-4; BNDB-4; mammals, animals)
SourceBos taurus (Bovine)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus 520A (MIC=10-300 µg/ml);##Gram-negative bacterium: Escherichia coli ML35 (MIC=10-300 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P46162
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed IDPubMed ID is not available, 8454635

Physicochemical Properties

Residues41
SequenceQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR
Molecular Weight4782.745
Grand Average of Hydropathy-0.241
Isoelectric Point11.174
Charge at pH 7.47.41
Secondary StructureHelix: 0.244, Turn: 0.268, Sheet: 0.073
Instability Index70.112
Aromaticity0.073

Similar Structure Search

Candidates based on structure

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