| ID | DRAMP02963 |
|---|---|
| Sequence | GRFRRLRKKTRKRLKKIGKV |
| Length | 20 |
| Name | PMAP-36(1-20) |
| Source | Sus scrofa (Pig) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
| Pathogen | Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=6 µM), Bacillus megaterium Bm11 (MIC=3 µM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=12 µM), E. coli ML35 (MIC=12 µM), S. enterica ser. Typhimurium ATCC 14028 (MIC=48 µM), Pseudomonas aeruginosa ATCC 27853 (MIC=3 µM).##Fungi: Candida albicans c.i. (MIC>64 µM). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 16128809 |
Physicochemical Properties
| Residues | 20 |
|---|---|
| Sequence | GRFRRLRKKTRKRLKKIGKV |
| Molecular Weight | 2525.147 |
| Grand Average of Hydropathy | -1.64 |
| Isoelectric Point | 12 |
| Charge at pH 7.4 | 11.542 |
| Secondary Structure | Helix: 0.250, Turn: 0.100, Sheet: 0.100 |
| Instability Index | 47.09 |
| Aromaticity | 0.05 |