| ID | DRAMP02971 |
|---|---|
| Sequence | RGGRLCYCRRRFCICV |
| Length | 16 |
| Name | Protegrin-2 (Protegrin 2; PG-2; pigs, mammals, animals) |
| Source | Sus scrofa (Pig) |
| Activity | Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram- |
| Pathogen | Gram-positive bacterium: Listeria moncyrogenes strain EGD (MIC>25 µg/ml);##Gram-negative bacterium: Escherichia coli ML-35 (MIC>25 µg/ml).##Yeast: Candida albicans strain 820 (MIC>25 µg/ml). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P32195 |
| PDB | 2MUH |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 8335113, 8250892 |
Physicochemical Properties
| Residues | 16 |
|---|---|
| Sequence | RGGRLCYCRRRFCICV |
| Molecular Weight | 1961.411 |
| Grand Average of Hydropathy | 0.044 |
| Isoelectric Point | 9.881 |
| Charge at pH 7.4 | 4.457 |
| Secondary Structure | Helix: 0.312, Turn: 0.125, Sheet: 0.062 |
| Instability Index | 78.669 |
| Aromaticity | 0.125 |