Basic Information

IDDRAMP02999
SequencePFKISIHL
Length8
NameJellein-1 (Jelleine-I; chain of Major royal jelly protein 1; Insects, animals)
SourceApis mellifera (Honeybee)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacteria: Staphylococcus aureus ATCC 6535 (MIC=10 µg/ml), S. saprophyticus (MIC=15 µg/ml), Bacillus subtilis CCT 2471 (MIC=10 µg/ml).##Gram-negative bacteria: Escherichia coli CCT 1371 (MIC=2.5 µg/ml), Enterobacter cloacae ACCT 23355 (MIC=10 µg/ml), Klebsiella pneumoniae ACCT 13883 (MIC=10 µg/ml), Pseudomonas aeruginosa ACCT 27853 (MIC=10 µg/ml).##Yeast: Candida albicans (MIC=2.5 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot O18330, Q548D6
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15203237, 9395329, 21516106

Physicochemical Properties

Residues8
SequencePFKISIHL
Molecular Weight954.166
Grand Average of Hydropathy0.762
Isoelectric Point9.181
Charge at pH 7.40.935
Secondary StructureHelix: 0.500, Turn: 0.250, Sheet: 0.125
Instability Index18.85
Aromaticity0.125

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.