Basic Information

IDDRAMP03000
SequenceTPFKISIHL
Length9
NameJellein-2 (Jelleine-II; chain of Major royal jelly protein 1; Insects, animals)
SourceApis mellifera (Honeybee)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacteria: Staphylococcus aureus ATCC 6535 (MIC=15 µg/ml), S. saprophyticus (MIC=10 µg/ml), Bacillus subtilis CCT 2471 (MIC=30 µg/ml);##Gram-negative bacteria: Escherichia coli CCT 1371 (MIC=15 µg/ml), Enterobacter cloacae ACCT 23355 (MIC=15 µg/ml), Klebsiella pneumoniae ACCT 13883 (MIC=15 µg/ml), Pseudomonas aeruginosa ACCT 27853 (MIC=15 µg/ml).##Yeast: Candida albicans (MIC=2.5 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot O18330, Q548D6
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15203237, 9395329, 21516106

Physicochemical Properties

Residues9
SequenceTPFKISIHL
Molecular Weight1055.27
Grand Average of Hydropathy0.6
Isoelectric Point8.441
Charge at pH 7.40.243
Secondary StructureHelix: 0.444, Turn: 0.222, Sheet: 0.111
Instability Index17.867
Aromaticity0.111

Similar Structure Search

Candidates based on structure

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