Basic Information

IDDRAMP03018
SequenceINMKASAAVAKKLL
Length14
NameMP-VB1 (Insects, animals)
Sourcevespine wasps Vespa bicolor
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.18723059] Gram-negative bacterium: Escherichia coli ATCC25922(MIC=15.0μg/ml), Escherichia coli 23A(MIC=15.0μg/ml), Escherichia coli 27A(MIC=60.0μg/ml), Pseudemonas aeruginosa 3A(MIC=15.0μg/ml), Pseudemonas aeruginosa 7A(MIC=120.0μg/ml), ;## Gram-positive bacterium: Staphylococcus aureus ATCC2592(MIC=3.75μg/ml), Staphylococcus aureus 6A(MIC=1.9μg/ml), Staphylococcus aureus 15A(MIC=3.75μg/ml);## Fungus: Candida albicans ATCC2002(MIC=15.0μg/ml)
Hemolytic Activity[Ref.18723059] MP-VB1 had almost no hemolytic activity of 1.7% and 2.7% against rabbit and human red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID18723059

Physicochemical Properties

Residues14
SequenceINMKASAAVAKKLL
Molecular Weight1457.823
Grand Average of Hydropathy0.671
Isoelectric Point10.302
Charge at pH 7.42.55
Secondary StructureHelix: 0.286, Turn: 0.143, Sheet: 0.500
Instability Index3.221
Aromaticity0

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