Basic Information

IDDRAMP03025
SequenceINLKAIAALAKKLL
Length14
NameMastoparan M
SourceVespa magnifica
ActivityAntimicrobial, Antibacterial, Anti-gram+, Anti-gram-
Pathogen[Ref.27591703] Gram-positive bacteria : Staphylococcus aureus isolates(MIC=6.0 ± 3.5 mg/L, MBC=6.0 ± 3.5 mg/L), Enterococcus faecalis isolates(MIC=5.3 ± 2.3 mg/L, MBC=6.7 ± 2.3 mg/L);##Gram-negative bacteria : Pseudomonas aeruginosa isolates(MIC=4.0 ± 3.5 mg/L, MBC=4.7 ± 3.0 mg/L), Acinetobacter baumannii isolates(MIC=2.7 ± 1.2 mg/L, MBC=3.3 ± 1.2 mg/L)
Hemolytic Activity[Ref.27591703] 0% hemolysis at 64 μg/ml against human red blood cells; 0% hemolysis at 32 μg/ml , 6% hemolysis at 64 μg/ml against sheep red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15935330, 27591703

Physicochemical Properties

Residues14
SequenceINLKAIAALAKKLL
Molecular Weight1479.892
Grand Average of Hydropathy1.157
Isoelectric Point10.302
Charge at pH 7.42.55
Secondary StructureHelix: 0.429, Turn: 0.071, Sheet: 0.571
Instability Index-2.843
Aromaticity0

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