Basic Information

IDDRAMP18665
SequenceINLKALAALAKKIL
Length14
NameMastoparan-L (MP-L; insects, arthropods, invertebrates, animals)
SourceVespula lewisii (Korean yellow-jacket isp) (Vespula flaviceps lewisii)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.27423268]Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=12.5 μM), Enterococcus faecalis ATCC 29212 (MIC=25 μM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=25 μM), Pseudomonas aeruginosa ATCC 27853 (MIC=50 μM), Klebsiella pneumoniae ATCC 13883 (MIC=12.5 μM), Acinetobacter baumannii ATCC 19606 (MIC=2.7 μM)
Hemolytic Activity[Ref.27423268]40% hemolysis at 10μM against rat red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P01514
PDB 1D7N
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID27423268

Physicochemical Properties

Residues14
SequenceINLKALAALAKKIL
Molecular Weight1479.892
Grand Average of Hydropathy1.157
Isoelectric Point10.302
Charge at pH 7.42.55
Secondary StructureHelix: 0.429, Turn: 0.071, Sheet: 0.571
Instability Index10.914
Aromaticity0

Similar Structure Search

Candidates based on structure

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