| ID | DRAMP03033 |
|---|---|
| Sequence | INWKGIAAMAKKLL |
| Length | 14 |
| Name | Mastoparan-like peptide 12a (Insects, animals) |
| Source | Vespa magnifica (Hornet) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
| Pathogen | [Ref.17046111]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=7.5 µg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=3.7 µg/ml);##Fungi: Candida albicans ATCC 2002 (MIC=3.7 µg/ml). |
| Hemolytic Activity | [Ref.16330062]Little hemolytic activity at 50 μg/ml against rabbit red blood cells |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P0C1M4 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 16330062, 17046111 |
Physicochemical Properties
| Residues | 14 |
|---|---|
| Sequence | INWKGIAAMAKKLL |
| Molecular Weight | 1556.956 |
| Grand Average of Hydropathy | 0.529 |
| Isoelectric Point | 10.302 |
| Charge at pH 7.4 | 2.55 |
| Secondary Structure | Helix: 0.357, Turn: 0.143, Sheet: 0.429 |
| Instability Index | -7.5 |
| Aromaticity | 0.071 |