Basic Information
| ID | DRAMP01208 |
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| Sequence | SIITMTKEAKLPQLWKQIACRLYNTC |
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| Length | 26 |
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| Name | Pleurain-A1 (Pleurain A1; Frogs, amphibians, animals) |
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| Source | Rana pleuraden (Yunnan pond frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.17764786]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=60 µg/ml), Helicobacter pylori NCTC 11637 (MIC=30 µg/ml);##Gram-positive bacteria: Bacillus dysenteriae (MIC=120 µg/ml), Staphylococcus aureus ATCC 2592 (MIC=15 µg/ml);##Yeast: Candida albicans ATCC 2002 (MIC=30 µg/ml).. |
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| Hemolytic Activity | [Ref:17764786] It has little hemolytic activity on red blood cells even with peptide concentration up to 200 μg/ml |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys20 and Cys26) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
A8DY01, A8DY00, A8DY02, A8DY03, A8DY04, A8DY09, A8DY10, A8DY15 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 17764786 |
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